The Investigation of the Efficacy of Some Antiseptics and Disinfectants to Vancomycin-Resistant Enterococci

نویسندگان

چکیده

Disinfection of contaminated material, surface and body parts with appropriate substances is one the most effective practices in preventing infection-colonization Vancomycin-Resistant Enterococci (VRE). In this study, 1/10 1/100 dilutions 5% sodium hypochlorite, 4% concentration chlorhexidine gluconate 0.1% 0.5% concentrations Akacid plus’s efficacy against VRE strains at 1, 5, 15 30 minutes was tested. Sixty-nine vancomycin-resistant E. faecium isolated from different samples between 2012 2014 were included study. The BD Phoenix 100® fully automated system used for identification detection vancomycin resistance. Quantitative Suspension Test method EN 1276 (March 2010) to evaluate bactericidal activities chemical disinfectants antiseptics European Union countries investigation disinfectant susceptibility strains. Five log10 decrease (105) number bacteria initial test suspension after using indicates that effective. it has been determined a dilution hypochlorite (bleach) on VREs all conditions. Effectiveness bleach significant dirty plus not any contact times we It observed least affected by changes environmental conditions minutes. Chlorhexidine (4%) ineffective clean just 1 minute, while 5th its effectiveness found be statistically same level as bleach. There no due changing conclusion, conditions, but cause hypochlorite. addition, increased time increased.

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ژورنال

عنوان ژورنال: Journal of molecular virology and immunology

سال: 2022

ISSN: ['2717-7874']

DOI: https://doi.org/10.46683/jmvi.2022.63